Low Blood Levels of Long-Chain n–3 Polyunsaturated Fatty Acids in US Hemodialysis Patients: Clinical Implications

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چکیده

منابع مشابه

Low blood levels of long-chain n-3 polyunsaturated fatty acids in US hemodialysis patients: clinical implications.

BACKGROUND Cardioprotective and other clinical benefits of long-chain n-3 polyunsaturated fatty acids (PUFA) are inversely related to dietary intake and hence blood content. We therefore investigated, in the first study of its kind, the blood content and distribution of these fatty acids in a large representative population of US hemodialysis patients. METHODS Frozen sera were obtained from 4...

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Blood levels of long-chain polyunsaturated fatty acids, aspirin, and the risk of colorectal cancer.

BACKGROUND N-3 fatty acids may decrease risk of colorectal cancer by inhibiting the cyclooxygenase-2 enzyme and production of proinflammatory eicosanoids derived from arachidonic acid (20:4n-6). Aspirin also inhibits the cyclooxygenase-2 enzyme and may share with n-3 fatty acids a potential mechanism to decrease the risk of colorectal cancer. METHODS We conducted a nested case-control analysi...

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Synthesis of long-chain polyunsaturated fatty acids in preterm newborns fed formula with long-chain polyunsaturated fatty acids.

BACKGROUND Docosahexaenoic acid (DHA) and arachidonic acid (AA) are long-chain polyunsaturated fatty acids (LCPs) that play pivotal roles in growth and neurodevelopment. OBJECTIVE We aimed to quantify the synthesis of LCPs in preterm infants fed infant formula containing LCPs. DESIGN Twenty-two preterm infants were randomly assigned to either the no-LCP group (fed formula without LCPs; n = ...

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Long-Chain Polyunsaturated Fatty Acids in Inborn Errors of Metabolism

The treatment of children with inborn errors of metabolism (IEM) is mainly based on restricted dietary intake of protein-containing foods. However, dietary protein restriction may not only reduce amino acid intake, but may be associated with low intake of polyunsaturated fatty acids as well. This review focuses on the consequences of dietary restriction in IEM on the bioavailability of long-cha...

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Significance of long chain polyunsaturated fatty acids in human health

In the last decades, the development of new technologies applied to lipidomics has revitalized the analysis of lipid profile alterations and the understanding of the underlying molecular mechanisms of lipid metabolism, together with their involvement in the occurrence of human disease. Of particular interest is the study of omega-3 and omega-6 long chain polyunsaturated fatty acids (LC-PUFAs), ...

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ژورنال

عنوان ژورنال: American Journal of Nephrology

سال: 2012

ISSN: 1421-9670,0250-8095

DOI: 10.1159/000343741